This article was originally published in 2023 and updated in April 2026 to reflect the latest information about Marijuana and Anesthesia.
Marijuana and anesthesia interactions continue to pose risks during and after dental and surgical procedures. While cannabis use doesn’t impact every person equally, it does influence how your body responds to certain medications used during and after treatment.
Our dentists at Asheville Dental break down what cannabis users have to know before a sedation appointment.
“I have certainly found that some marijuana users are more difficult to numb. It can be frustrating for the patient. It’s helpful that research is emerging that explores the link between marijuana and anesthesia.” —Dr. Grant Dasher
Is Marijuana Still a Schedule 1 Drug?
As of 2026, North Carolina has not legalized recreational marijuana use. However, there is an ongoing federal review process to reclassify it to Schedule III. That change has not been fully implemented, so there are research limitations, and more studies are emerging.
Understanding Marijuana and Anesthesia
Recent research shows cannabis users may require higher doses of propofol, a common anesthesia drug, to be properly sedated and pain-free during treatments. Some reported doses were 15% to 30% higher than those needed for non-users. While the exact reason for this is still unknown, evidence suggests that:
- Dental professionals have noticed that cannabis users are harder to numb during procedures.
- Marijuana use can affect how the body experiences pain and sometimes lead to a higher need for pain medications post-treatment.
- Using cannabis can increase heart rate and affect blood pressure.
- Smoking cannabis may irritate the airways, which can make sedation more difficult.
- Cannabis use may raise the risk of bleeding, infections, and other complications after dental treatments.
Before coming to an appointment that requires anesthesia or sedation, we highly encourage you to avoid any cannabis use for at least 72 hours (depending on the particular procedure, we may recommend a longer time). This includes inhalation, edibles, and synthetic mind-altering substances.
Ensuring Safety and Comfort at Asheville Dental
Our Asheville Dental team provides a judgment-free space for open conversations about marijuana so we can tailor your dental care appropriately and prioritize your safety and comfort.
Your privacy is always respected, and transparency helps us ensure the best outcomes for your dental health. Have questions? Contact us today!
